Holli Jacoby is one of Williamstown, West Virginia's glass jewelry artists. She spends her days painting intricate nature scenes on beads and pendants at the renowned factory along the Ohio River. After work hours, though, she hides away in her grandma's cottage throwing clay as a way to battle the effects of her bipolar disorder. Abandoned by her family, and marked as being "off" by those who have dealt with her, Holli avoids personal contact with everyone except Brenna, her life-long friend and anchor. Isaac Bradshaw's "free" time is split between the local bar playing pool with his buddies and helping his parents due to his father's declining health. An easy-going welder with a love of adventure, Isaac is drawn to Holli's fire and mystery, but her roller coaster emotions and her asocial tendencies might be more than he's willing to handle. When tragedy strikes and her stability disintegrates, their relationship is strained to its core.