This volume provides a comprehensive and authoritative overview of a century of research on synaptic structure and function culminating in the most recent work. Written by leading experts in the field, the book should be of interest to a broad range of neuroscientists, including those studying the cellular and molecular mechanisms of synaptic transmission, learning and memory, neuronal plasticity, neurotransmitters and synaptic morphology. It should also be a useful reference for students and biomedical professionals in all areas of neuroscience.